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2020 Center on the Physics of Cancer Metabolism

A fantastic, productive  site visit this week–approximately 60 faculty and trainees from MD Anderson, & Weill Cornell–sharing presentations and posters on progress w/the NCI.

Due to the COVID-19 crisis most outside visitors including NCI staff as well as most of our Advisory Board attended the meeting virtually via videoconference. One of our Advisory Board Members (Amato Giaccia) attended the meeting in person. Together with Douglas Yee, Director of the Masonic Cancer Center at the Uof Minnesota and Clare Waterman, Director, Cell and Developmental Biology Center at the National Heart, Lung and Blood Institute of the National Institutes of Health, he provided important feedback and insights into future directions for our Center. The goal of the meeting was to provide a broad overview of the Center and for students and participating faculty to meet in person and discuss new and ongoing collaborations. Activities included, presentations, networking meals and a poster session. Our next retreat will be planned again in conjunction with our yearly NCI Site Visit in 2021.



2019 Center on the Physics of Cancer Metabolism

A fantastic, productive  site visit this week–approximately 60 faculty and trainees from MD Anderson, UCSF  & Weill Cornell–sharing presentations and posters on progress w/the NCI.

A special thanks goes to all poster presenters. The posters that were selected for the People’s Choice award are below. The winners will receive a $100 gift card and be invited to present their poster at the ACS Gala for a chance to win $500.

Nanoparticle Manipulation in Microfluidic-Surface Acoustic Wave Resonators
. Prateek Sehgal and Brian J. Kirby

PEG-Heparin Hydrogels to Study the Combined Effects of ECM Physical Properties and IL-8 on Breast Cancer Cells.  Brittany Schutrum, Jason Freedman, Katharina Wittmann, Jana Sievers, Giorgio Inghirami, Benjamin D. Hopkins, Lewis C. Cantley, Uwe Freudenberg, Carsten Werner, Claudia Fischbach



2 Pilot Projects  for Year 3 have been awarded and started October 15, 2018

Hemostasis at the Crossroad of Immunity and Cancer

Project Investigators: Tracy Stokol,  Cynthia Leifer, Associate

Additional Collaborators : Nozomi Nishimura, Teresa Southard

Novel Affinity Reagents for Analysis of Tumor Microvesicles and Their Metabolically Regulated Glycome (competitive renewal of Year 1 Pilot Project)

Project Investigators: Matt DeLisa, Matthew Paszek

Additional Collaborators: Sachdev Sidhu, Wesley Legant






Article in Science by Alexandra McGregor and Peter DelNero now available online

2 Pilot Projects  for Year 2 have been awarded and started September 15, 2017

Mechanisms of Copper Depletion in TNBC Metastasis- From Bedside to the Bench

Project Investigators: Vivek Mittal, Claudia Fischbach

Additional Collaborators: Linda Vahdat (Weill Cornell Medicine) Noah Elias Dephoure (Weill Cornell Medicine)

Single-Cell Deep-Profiling of Signaling and Genomic Alterations Mediating the Evolution of Chemo-Therapeutic Resistance in Breast Cancer

Project Investigators: Ben Cosgrove

Additional Collaborators: Olivier Elemento, (Weill Cornell Medicine)


February 9, 2017

Collaboration Employs New Strategies to Study the Spread of Cancer

 click here to view video


January 23, 2017

2 Pilot Projects have been awarded to start January 1, 2017

Novel Affinity Reagents for Analysis of Tumor Microvesicles and Their Metabolically Regulated Glycome

Matt DeLisa and Matt Paszek, Cornell University 

Revealing Mechanisms of Microvesicle Biogenesis in Breast Cancer via in situ Microscopy

Lara A. Estroff; Cornell University  


January 23, 2017

Center on the Physics of Cancer Metabolism

Inaugural retreat of our Center brought together more than 50 scientists from Ithaca, New York, San Francisco, and Houston to discuss science across all participating institutions.

A special thanks goes to all poster presenters. The posters that were selected by the jury for this year’s $250 poster award were:

Mammary Window Imaging of Breast Carcinoma Cell Invasion in Vivo, Olga Ilina, Leonard Campanello, Pavel Gritsenko, Chenlu Wang, Rachel Lee, Manon Vullings, Beerling E, Antoine A. Khalil, Michael C Weiger, Paul Span, Peter Bult, Jacco van Rheenen, Wolfgang Losert, Peter Friedl

A Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Motility, Carolyn Shurer, Marshall Colville, Shelby Head, Vivek Gupta, Matthew Paszek



January 23, 2017

Peter DelNero, Ph.D. student (BME), has been selected for a 2017 K. Patricia Cross Future Leaders Award from the Association of American Colleges and Universities. The award recognizes graduate students who show exemplary promise as future leaders of higher education. It will be presented at the association’s annual meeting later this month. 

Peter DelNero is a PhD student in the Fischbach lab. He is a member of the leadership team for the Cancer Brainstorming Club, and is one of the students involved in creating the PS-OC partnership with the Cancer Resource Center of the Finger Lakes.

October 24, 2016

A team of PSOC members participated in this year’s Walkathon, an annual fundraiser for the Cancer Resource Center of the Finger Lakes in Ithaca. They braved the elements and were able to raise over $3,000 to help support the local cancer community.










August, 2016

Grant Launches Center on the Physics of Cancer Metabolism

Cornell Chronicle

By Syl Kacapyr

The mechanisms controlling how breast cancer develops, spreads to other parts of the body and responds to therapy remain poorly understood, but researchers from the College of Engineering and Weill Cornell Medicine hope to change that through the Center on the Physics of Cancer Metabolism – a new multi-institutional translational research unit to be established with a National Cancer Institute grant.

On Aug. 25 New York Sens. Kirsten Gillibrand and Charles Schumer announced first-year funding for the center of $1.9 million. The grant could total $9.3 million over five years.

Led by Claudia Fischbach-Teschl, associate professor of biomedical engineering at Cornell University, and Dr. Lewis Cantley, the Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine in New York City, other partners include researchers from Memorial Sloan Kettering Cancer Center, the University of Texas MD Anderson Cancer Center and the University of California, San Francisco. The partnership will also foster collaborations across the Ithaca campus among researchers from the College of Engineering, the College of Arts and Sciences and the College of Veterinary Medicine.

The goal of the center is to combine the strengths of different interdisciplinary research groups to gain unprecedented understanding of the biological and physical mechanisms regulating how tumors function and metastasize, or spread, in the human body’s microenvironment.

Cantley’s expertise in cancer metabolism, which has led to several breakthroughs in the field, dovetail with Fischbach-Teschl’s acumen in engineering of cancer models to enable the team to explore tumor development, progression and metastasis from a completely new perspective. Complemented by other investigators’ expertise in micro- and nanofabrication, imaging and computational approaches, they can monitor and predict tumor metabolism and cell migration, and test drugs or other therapies in a patient-specific manner.

For full article click here.

August 25, 2016

The NY State Senator’s office announces our new Center on their website.